The DNA Lounge is a popular late-night San Francisco nightclub, founded in the 1980s, which caters particularly to the digerati scene. It was purchased in 2000 by celebrated hacker Jamie Zawinski, who spearheaded a successful grassroots effort to maintain its many late-night permits. At the time, his plan was to make it a "total nerd space".

When not functioning as a nightclub, the DNA Lounge regularly hosts hacker conventions such as CodeCon.

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